Removing API residues from processing tools in sterile areas is a serious validation issue especially for cyto-toxic compounds.

The Sequence below highlights this issue as a user required three distinct wipe passes with a standard clean room grade polyester wiper in order to achieve a surface free of Arsenic residue. But validation testing showed instances when Arsenic was still present.

High levels of Arsenic found after first polyester wiping pass

The second motion with polyester wipers shows reduced Arsenic levels

The third polyester wiper indicates an Arsenic free surface

More rigorous inspection techniques showed Arsenic contamination on the surface. MiraWIPE'S® unique fiber structure enables improved cleaning efficacy enabling the user to achieve validated cleanliness with only 2 wiper passes.