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Cleaning GMP Cleanrooms: Ultrapure Water vs. 70% IPA

by | Jan 31, 2024

Why You Shouldn't Drink Ultra Pure Water - Advanced Water Solutions

In the world of cleanroom maintenance, choosing the right cleaning agent is crucial. Two popular contenders are ultrapure water and 70% isopropyl alcohol (IPA). Each has its merits, and understanding their strengths and limitations is essential for effective cleanroom hygiene.

The Traditional Preference: 70% IPA

Isopropyl alcohol (IPA) has long been the go-to choice for cleanroom disinfection. Here’s why:

  1. Disinfection Power: IPA is a potent disinfectant. It effectively kills bacteria, viruses, and fungi, making it ideal for maintaining sterile environments.
  2. Quick Evaporation: IPA evaporates rapidly, leaving surfaces dry and ready for use. This quick-drying property is especially valuable in time-sensitive cleanroom operations.
  3. Non-Residue: Unlike other disinfectants, IPA doesn’t leave visible residues behind. It ensures that surfaces remain clean and particle-free.

The Role of Water in Cleanroom Cleaning

While IPA has its advantages, there are scenarios where ultrapure water shines:

  1. Rinsing Sporicides and Disinfectants: Some disinfectants, such as bleach and sporicides, are more soluble in water than in IPA. Water flushes away these chemicals effectively.
  2. Compatibility with Sensitive Materials: In cleanrooms with sensitive materials or electronics, ultrapure water is a safer choice. It won’t harm delicate components or leave behind any chemical residues.

Introducing Foamtec’s MiraSAT: The Best of Both Worlds

Foamtec International understands the unique needs of cleanroom facilities. Our MiraSAT pre-saturated cleanroom wipes combine the benefits of ultrapure water and microfiber technology:

  1. Ultraclean Water: MiraSAT wipes are presaturated with ultrapure water, ensuring the highest level of cleanliness. No impurities, no contaminants—just pure cleaning power.
  2. Microfiber Efficiency: The microfiber fabric in MiraSAT wipes traps particles and contaminants effectively. It’s gentle on surfaces yet tough on residues.
  3. Streak-Free and Dry: Like 70% IPA, MiraSAT leaves surfaces streak-free and dry. Say goodbye to wet spots and lingering moisture.
  4. Sterile and Non-Sterile Options: Whether you need sterile wipes for critical environments or non-sterile wipes for routine cleaning, MiraSAT has you covered.


Regarding cleanroom maintenance, the choice between ultrapure water and IPA depends on the specific task. However, with Foamtec’s MiraSAT wipes, you get the best of both worlds: effective cleaning, residue-free surfaces, and the confidence that your cleanroom meets the highest standards.

Discover the MiraSAT advantage and elevate your cleanroom hygiene today!

MiraSAT™ UPW Wipers